PULMONARY ARTERIAL HYPERTENSION
Pulmonary arterial hypertension (which may be referred to as “PAH”, “PPH”-primary pulmonary hypertension, or “IPAH”-idiopathic pulmonary arterial hypertension) is a rare, serious, very complex condition in which the “blood pressure” in the pulmonary arteries is elevated. Unless it is treated, it eventually leads to heart failure. Learn more here.
CAUSES AND RISK FACTORS
Pulmonary hypertension can fall into one of 5 classes and even with modern knowledge and advancements, the causes and pathophysiology are poorly understood. Strictly speaking, IPAH (the currently preferred designation) is “pulmonary hypertension with no known cause”. However, within its classification “group”, we also find PAH associated with genetic defects, certain infections (including HIV), and other specific underlying conditions, because they share clinical features.
• Most common symptoms
• Shortness of breath/trouble breathing
• Recurrent fainting
• Other symptoms
• weight loss
• chest pain, and right upper quadrant pain
• Cough/coughing up blood
Women are more likely to be symptomatic than men.
DIAGNOSIS AND TESTS
• Diagnosis is made after extensive testing by a cardiologist, usually including imaging of the heart and lungs, and heart catheterization.
• Medications used for treatment include common oral medications used for other cardiac conditions (including drugs to prevent clots, and control heart rhythm, and reduce swelling) as well as very specialized drugs for IPAH which may be inhaled or given by infusion (IV). Oxygen therapy may be necessary as well. There are also surgical options, including lung transplant, available for patients who do not respond to medication.
• While there is no cure for IPAH and without treatment, the estimated 3 year survival rate is only about 41%, studies on what to expect with newer treatments and combinations of drugs are ongoing and look promising.
Drug information for this condition is made available by Factor One Source FAST Pharmacy upon request by emailing email@example.com directly, or by submitting an inquiry through our Contact Page.
MEDICATIONS DISPENSED THROUGH FOSRX/FAST:
- Epoprostenol Sodium
- 01 Apr 2016
- FOSRX/FAST Services